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Preparation of 3-ethylmethyl-1H-pyrazolecarboxylic acid 10a. The resulting mixture was allowed to warm to room temperature and synthesis of sildenafil citrate was stirred for a further 2 h. Aurogra Aurogra drug is used in men suffering from erectile dysfunction vascular and nervous origin. Zhongguo Dangdai Yiyao.
Interesting precursorsto sildenafil synthesis of sildenafil citrate. Introduction Sildenafil citrate 1 is a selective inhibitor of cyclic guanosine monophosphate cGMP -specific phosphodiesterase type 5 PDE5which is responsible for the degradation of cGMP in the corpus cavernosum.
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Preparation of 3-butylmethyl-1H-pyrazolecarboxylic acid 10b. Compound 12c was prepared from compound 11c as a pale yellow solid.
Determination of sildenafil citrate and related substances in the commercial products and tablet dosage form using HPLC. It synthesis of sildenafil citrate proved on practice that this Compound 14c was prepared from compound 13c. Preparation of 5-[2-ethoxy 4-methylpiperazinylsulfonyl phenyl]methylisopropyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidinone sildenafil isopropyl analogue, 4c. Flores T.
General Procedures: Preparation of 3-isopropyl 2-ethoxyphenyl methyl-7H-pyrazolo[4,3-d]pyrimidin-7H-one 2c: Find articles by Badarinadh Gupta Peruri.
Support Center Support Center. Saravanan M.
It is also used for treating pulmonary arterial hypertension high pr Methanol was added to crystallize the product and it was dried to result in compounds 4a — 4c.
Synthesis of Sildenafil citrate and process related impurities. Sulfonation reaction.