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Recruitment Status: Sildenafil exposure in neonates with pulmonary hypertension after administration via a nasogastric tube.
Some implications for paediatric anaesthesia dosing. John P Kinsella. There were no further changes beyond min in controls.
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Paroxetine
Robin Steinhorn. Milrinone may have specific benefits as an 'inodilator', as prolonged exposure to iNO plus oxygen may activate phosphodiesterase PDE 3A.
Oral Sildenafil was discontinued in one infant due to systemic hypotension. Oral sildenafil in infants with persistent pulmonary hypertension of the newborn: The median metabolite-to-parent ratio was higher in infants receiving co-medications that can induce cytochrome P CYP enzymes 5.
Jonas Pedersen. Treatment of pulmonary arterial hypertension in children. Ghazwan Butrous. Crit Care Med.
Twenty-three infants were included in the study. None of the patients had significant systemic hypotension. The starting dose of oral sildenafil is 0.
This publication presents the results of extensive literature reviews, discussions, and formal scoring of recommendations iv sildenafil for neonates the care of children with pulmonary hypertension. Neonatal pulmonary hypertension is associated with meconium aspiration syndrome, sepsis, asphyxia, respiratory distress syndrome, congenital diaphragmatic hernia, congenital heart disease, or bronchopulmonary dysplasia. Christian Apitz Heiner Latus.
Listing a study does not mean it has been evaluated by the U. Studies were commenced within 7 h of separation from iv sildenafil for neonates. PPHN can largely be thought of as one of three types: